Fig. 4

Representative histology of rectal carcinoma showing dual differentiation toward enteroblastic and neuroendocrine features in the same cells. a Tumor cells partially arranged in glandular patterns and partially showed solid growth (H&E × 40). SALL4 (b) was immunohistochemically positive in a part of the tumor cells, and synaptophysin (c) was also positive in a part of them. Expression of SALL4 (b) and synaptophysin (c) was overlapping in some tumor cells