Table 1 Risk factors for lymph node metastasis of pancreatic neuroendocrine neoplasm
From: Reconsideration of operative indications in pancreatic neuroendocrine neoplasms
Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|
Lymph node positive (n = 17) | Lymph node negative (n = 70) | P value | Odds ratio | 95% CI | P value | ||
Age (median, years) | 50 (34–78) | 62 (18–84) | 0.113 | ||||
Male / Female | 4/13 | 38/32 | 0.110 | ||||
Tumor size (median, cm) | 4.0 (0.8–13.5) | 1.5 (0.3–3.7) | < 0.001 | ≧ 2.0 cm | 10.8 | 3.0–100.0 | 0.001 |
Multiple lesions | 5 (29.4%) | 6 (8.6%) | 0.020 | 8.7 | 1.5–52.0 | 0.018 | |
Hereditary syndrome | 3 (17.6%) | 10 (14.3%) | 0.727 | ||||
Preoperative symptoms | 7 (41.2%) | 18 (25.7%) | 0.206 | ||||
Pathologically functional PNEN | 5 (29.4%) | 20 (28.6%) | 0.945 | ||||
Grade (G1 vs G2/G3) | 6 (35.3%) | 31 (44.3%) | 0.444 | ||||
Ly (0/1 vs 2/3) | 2 (11.8%) | 5 (7.1%) | 0.540 | ||||
V (0/1 vs 2/3) | 3 (17.6%) | 13 (18.6%) | 0.910 | ||||
Ne (0/1 vs 2/3) | 2 (11.8%) | 5 (7.1%) | 0.540 | ||||
Recurrence | 9 (52.9%) | 7 (10.0%) | < 0.001 | ||||