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Table 2 Surgery, perioperative, and postoperative outcomes

From: Is there a role for lung surgery in initially unresectable non-small cell lung cancer after tyrosine kinase inhibitor treatment?

Variable

n (%)/[range]

P value

Surgery, (VATS)

 

0.603

 Lobectomy

14 (73.7)

   n= RUL/RML/RLL/LUL/LLL

3/1/5/2/3

 Sublobar resection

5 (26.3)

  n=Trisegmentectomy/lingulectomy/subsegmentectomy/Wedge resection

2/1/1/1

Number of lymphadenectomy, median

20 [5-38]

 

Complete resection

 

1.000

 R0

17 (89.5)

 R2

2 (10.5)

Duration of surgery, median minutes

180 [60-380]

0.020

Blood loss, median ml

40 [10-550]

0.049

Postoperative complications

 

0.614

 Bleeding

1 (5.3)

 Thoracic empyema

1 (5.3)

 Nil

17 (89.5)

30-day postoperative mortality

0 (0)

 

Median time to relapse, months

13 [6-41]

 

Relapse

 

<0.001

 Alive without relapse

10 (52.6)

 Alive with relapse

2 (10.5)

 Died with relapse

7 (36.8)

T790M status

  

 Positive

1 (5.3)

 Negative

1 (5.3)

 Unknown/not done

17 (89.4)

Recurrence pattern

 

<0.001

 Intrathoracic recurrence/metastases

2 (10.5)

 Distant metastases

3 (15.8)

 Intrathoracic and distant metastases

4 (21.1)

 Nil

10 (52.6)

Postoperative adjuvant therapy

 

0.129

 TKI

13 (68.4)

 Non-TKI

6 (31.6)

  1. VATS video-assisted thoracoscopic surgery, RUL right upper lobe, RML right middle lobe, RLL right lower lobe, LUL left upper lobe, LLL left lower lobe, TKI tyrosine-kinase inhibitor