Short-and long-term outcomes of laparoscopic versus open gastrectomy in patients with gastric cancer: a systematic review and meta-analysis of randomized controlled trials

Lei, Xiaokang; Wang, Yinkui; Shan, Fei; Li, Shuangxi; Jia, Yongning; Miao, Rulin; Xue, Kan; Li, Zhemin; Ji, Jiafu; Li, Ziyu

doi:10.1186/s12957-022-02818-5

Table 1 Characteristics of the included studies

From: Short-and long-term outcomes of laparoscopic versus open gastrectomy in patients with gastric cancer: a systematic review and meta-analysis of randomized controlled trials

Number	Studies	Country	Centers	Study period		Patients		Gender
				Start	End	LG	OG	LG		OG
				Start	End	LG	OG	Male	Female	Male	Female
1	Cai et al. (2011) [21]	China	Single-center	2008.3	2009.12	49	47	39	10	37	10
2	Chen et al. (2012) [46]	China	Multi-centers	2009.1	2011.5	41	41	20	21	21	20
3	Cui et al. (2015) [20]	China	Single-center	2010.1	2012.12	128	142	88	40	98	44
4	Hayashi et al. (2005) [32]	Japan	Single-center	1999.12	2001.11	14	14	9	5	13	1
5^a	Hu et al. (2016) [45]	China	Multi-centers	2012.9	2014.12	519	520	380	139	346	174
5^a	Huang et al. (2022) [34]	China	Multi-centers	2012.9	2014.12	519	520	380	139	346	174
5^a	Yu et al. (2019) [38]	China	Multi-centers	2012.9	2014.12	519	520	380	139	346	174
6	Huscher et al. (2005) [5]	Italy	Single-center	1992.11	1996.2	30	29	18	12	21	8
7	Hyung et al. (2020) [37]	Republic of Korea	Multi-centers	2011.11	2015.4	492	482	351	141	335	147
8^a	Katai et al. (2017) [43]	Japan	Multi-centers	2010.3.15	2013.11.29	457	455	289	173	275	184
8^a	Katai et al. (2020) [36]	Japan	Multi-centers	2010.3.15	2013.11.29	457	455	289	173	275	184
9^a	Kim et al. (2008) [30]	Republic of Korea	Single-center	2003.7	2005.11	82	82	47	35	52	30
9^a	Kim et al. (2013) [29]	Republic of Korea	Single-center	2003.7	2005.11	82	82	47	35	52	30
10	Kim et al. (2010) [47]	Republic of Korea	Multi-centers	2006.1.1	207.7.19	179	61	116	63	111	52
11^a	Kim et al. (2016) [44]	Republic of Korea	Multi-centers	2006.2.1	2010.8.31	644	612	425	219	412	200
11^a	Kim et al. (2019) [41]	Republic of Korea	Multi-centers	2006.1.5	2010.8.23	673	686	448	225	458	228
12	Kitano et al. (2002) [33]	Japan	Single-center	1998.10	2001.3	14	14	9	5	8	6
13	Lee et al. (2005) [31]	Republic of Korea	Single-center	2001.11	2003.8	24	23	11	13	15	8
14	Lee et al. (2019) [40]	Republic of Korea	Multi-centers	2011.11	2015.4	513	498	370	143	346	152
15	Li et al. (2019) [14]	China	Single-center	2015.4.23	2017.11.16	47	48	33	14	33	15
16	Liu et al. (2020) [12]	China	Single-center	2017.1	2018.10	105	109	75	30	80	29
17	Park et al. (2018) [42]	Republic of Korea	Multi-centers	2010.6	2011.10	100	96	69	31	65	31
18	Sakuramoto et al. (2013) [28]	Japan	Single-center	2005.10	2008.2	31	32	14	17	7	25
19	Sayed et al. (2021) [22]	Egypt	Single-center	2017.1	2019.12	16	20	13	7	11	5
20^a	Shi et al. (2018) [24]	China	Single-center	2010.1	2012.6	162	160	120	42	105	55
20^a	Shi et al. (2019) [23]	China	Single-center	2010.1	2012.6	161	156	120	41	101	55
21	Takiguchi et al. (2013) [27]	Japan	Single-center	2003.7	2006.1	20	20	12	8	13	7
22	van der Veen et al. (2021) [35]	Netherlands	Multi-centers	2015	2018	115	110	68	47	72	38
23	van der Wielen et al. (2021) [13]	Netherlands	Multi-centers	2015.1	2018.6	47	49	28	19	32	17
24	Wang et al. (2019) [39]	China	Multi-centers	2014.3	2017.8	222	220	144	78	133	87
25	Yamashita et al. (2016) [26]	Japan	Single-center	2005.1	2008.2	31	32	14	17	7	25
26	Zhou et al. (2017) [25]	China	Single-center	2012	2015	100	100	50	50	50	50

^aThese articles reported the results of the same study from the same authors or institutions

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