Table 4 Predictive factors of capsule invasion in PTC
From: HIF-1α and Caspase-3 expression in aggressive papillary thyroid carcinoma
Parameter | PTCs with/without capsule invasion | p-value | |
|---|---|---|---|
Yes (n = 48) | No (n = 22) | ||
Gender | 0.128 | ||
Female | 42 (72.4%) | 16 (27.6%) | |
Male | 6 (50.0%) | 6 (50.0%) | |
Age (year) | 0.288 | ||
< 45 | 24 (63.2%) | 14 (36.8%) | |
≥ 45 | 24 (75.0%) | 8 (25.0%) | |
Tumor size (cm) | 0.002* | ||
< 1 | 18 (51.4%) | 17 (48.6%) | |
≥ 1 | 30 (85.7%) | 5 (14.3%) | |
BRAFV600E mutation | 16 (69.6%) | 7 (30.4%) | 0.900 |
PTC subtype | 0.686 | ||
FVPTC | 25 (73.5%) | 9 (26.5%) | |
CVPTC | 16 (64.0%) | 9 (36.0%) | |
TCV | 7 (63.6%) | 4 (36.4%) | |
HIF-1α+ | 33 (78.6%) | 9 (21.4%) | 0.027* |
Caspase-3+ | 20 (76.9%) | 6 (23.1%) | 0.247 |