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Fig. 4 | World Journal of Surgical Oncology

Fig. 4

From: AXL, along with PROS1, is overexpressed in papillary thyroid carcinoma and regulates its biological behaviour

Fig. 4

Effect of different concentrations of R428 on B-CPAP cell migration. The B-CPAP cell line was cultured and treated with the AXL inhibitor R428 at various concentrations (0.5 µmol/L, 1 µmol/L, 2 µmol/L), and the no R428-treated group was used as the control group. The scratch assay was used to evaluate cell migration in each group. The graph taken by inverted microscopy indicates that the scratching area of the experimental groups treated with R428 was not decreased compared with that of the control group (A). Data were processed using ImageJ software, and the cell migration rate was finally quantified. The column chart further illuminated that there were significant differences among the serial experimental groups and the control group (B). (**p < 0.01 compared to the control group)

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