Fig. 3

Forest plot of hazard ratios for the time from baseline to first deterioration in the Quality of Life Questionnaire Core 30 items on quality of life (A), physical function (B), pain (C), and role function (D). A Random effect: P = 0.013; Egger’s test: P = 0.057; Begg’s test: P = 0.027. B Random effect: P = 0.000; Egger’s test: P = 0.020; Begg’s test: P = 0.089. C Random effect: P = 0.000; Egger’s test: P = 0.226; Begg’s test: P = 0.308. D Random effect: P = 0.012; Egger’s test: P = 0.293; Begg’s test: P = 0.308