Development and validation of an extended Cox prognostic model for patients with ER/PR+ and HER2− breast cancer: a retrospective cohort study

Table 4 Prognostic factors, coefficients, hazard ratios, and P-values of the Z-tests in model 1

Variable	Prognostic factor	Coefficient	HR (95% CI)	p-value
x₁	Histological grade (I, II, III)	1.380	3.976 (1.851, 8.843)	< 0.001
x₂	N status (0, 1, 2, 3)	1.010	2.746 (1.959, 3.849)	< 0.001
x₃	Ki67 status (60%)	1.643	5.172 (2.288, 11.691)	< 0.001
x₄	PR status (20%)	−0.949	0.387 (0.181, 0.826)	0.014
x₅	Age (55 years)	1.040	2.828 (1.285, 6.222)	0.01

HR hazard ratio, CI confidence interval. Ki67 status (60%), a binary variable that is one if Ki67 is no less than 60% and zero otherwise. PR status (20%), a binary variable that is one if PR is no less than 20% and zero otherwise. Age (55 years), a binary variable that is one if age is no less than 55 years and zero otherwise

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