Fig. 3

Circ_0000808 acted as miR-1827 sponge. A Venn diagram showed the targeted miRNAs of circ_0000808 predicted by both CircInteractome software and circBank software. B The expression of miR-1827 in NSCLC tumor tissues and adjacent normal tissues was measured by qRT-PCR. C The miR-1827 expression in NSCLC cells (A549 and NCI-H1299) and BEAS-2B cells was detected by qRT-PCR. D The sequences of circ_0000808 WT/MUT vectors were shown. E The transfection efficiency of miR-1827 mimic was confirmed by detecting miR-1827 expression using qRT-PCR. Dual-luciferase reporter assay (F-G) and RIP assay (H-I) were used to assess the interaction between circ_0000808 and miR-1827. **P < 0.01, ***P < 0.001