Table 4 Univariate and multivariate Cox proportional analysis of factors affecting overall survival in patients with peritoneal metastases from colorectal cancer
Factor | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p- value | |
Liver metastases | ||||
No | 1 (ref) | 1 (ref) | ||
Yes | 1.88 (1.04–3.39) | 0.037 | 2.52 (1.36–4.65) | 0.003 |
PCI-score | ||||
≤ 20 | 1 (ref) | 1 (ref) | ||
≥ 20 | 3.94 (2.53–6.14) | < 0.001 | 2.61 (1.53–4.44) | < 0.001 |
Signet ring cells | ||||
No | 1 (ref) | 1 (ref) | ||
Yes | 2.16 (1.33–3.50) | 0.002 | 0.67 (0.40–1.14) | 0.140 |
Open-close | ||||
No | 1 (ref) | 1 (ref) | ||
Yes | 5.99 (3.67–9.73) | < 0.001 | 4.16 (2.30–7.50) | < 0.001 |
MDC decision to surgery | ||||
≤ 34 days | 1 (ref) | |||
≥ 35 days | 1.34 (0.89–2.02) | 0.163 | ||
CPM diagnosis to surgery | ||||
≤ 58 days | 1 (ref) | |||
≥ 59 days | 1.04 (0.69–1.57) | 0.843 | ||
Time period | ||||
June 2012–December 2016 | 1 (ref) | |||
January 2017–December 2019 | 0.79 (0.52–1.21) | 0.285 | ||