Fig. 5

Microscopic aspects of special HCC variants. a A macrotrabecular massive subtype showed trabeculae > 10 cells in thickness (IHC, 100×). b A clear cell subtype showed sheets of hepatocytes contained high glycogen and lipid content (IHC, 100×). c A clear cell subtype showed focal fatty changes (IHC, 100×). d A clear cell subtype showed severe fatty changes (IHC, 100×). e A steatohepatitic subtype showed a triad of fatty change, intra-tumoral fibrosis, and inflammation (IHC, 100×). f A steatohepatitic subtype showed Mallory hyaline bodies (IHC, 200×). g A scirrhous subtype showed compressed cords of hepatocytes within desmoplastic stroma (IHC, 100×). h A FLC variant showed hepatocytes with abundant eosinophilic cytoplasm, prominent eosinophilic nucleoli separated by lamellated collagen bundles (IHC, 100×). i A FLC showed intra-tumoral pale bodies (IHC, 200×)