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Table 5 Logistic regression analysis of APOE gene polymorphisms for different tumors

From: Effects of APOE gene ε4 allele on serum lipid profiles and risk of cardiovascular disease and tumorigenesis in southern Chinese population

   Tumor versus control Tumor + CVD versus control
Allele Adjusted OR 95% CI p-value Adjusted OR 95% CI p-value
Digestive system ε2 1.6 0.71–3.6 0.26 1.22 0.39–3.78 0.73
ε3 0.14 0.02–1.27 0.08 0.11 0.004–2.81 0.18
ε4 2.19 1.0–4.76 0.049 2.77 1.05–7.3 0.039
Respiratory system ε2 1.89 0.71–5.01 0.20 1.35 0.41–4.48 0.63
ε3 0.17 0.02–1.89 0.15 1.08 0.01–82.23 0.97
ε4 2.93 1.29–6.63 0.01 4.15 1.48–11.7 0.007
Reproductive system ε2 0.41 0.06–3.0 0.38 0.35 0.03–4.44 0.42
ε3 - - - - - -
ε4 0.80 0.12–5.34 0.82 4.51 0.87–23.45 0.07
Endocrine system ε2 3.13 0.50–19.67 0.22 0.25 0.01–5.37 0.38
ε3 0.04 0.00–3.98 0.17 - - -
ε4 0.74 0.07–7.73 0.80 2.97 0.37–23.84 0.31
Nervous system ε2 3.19 0.29–34.52 0.34 - - -
ε3 - - - - - -
ε4 0.76 0.01–59.76 0.9 - - -
Urinary system ε2 - - - - - -
ε3 - - - - - -
ε4 2.53 0.19–33.37 0.48 3.9 0.45–33.61 0.22
Circulatory system ε2 0.92 0.08–10.78 0.95 - - -
ε3 0.01 0.000–0.63 0.03 - - -
ε4 - - - - - -
  1. Adjusted OR Adjusting the traditional factors including gender, age, smoking, TG, TC, LDL-C, HDL-C, SBP, and DBP