Fig. 1From: A progressive and refractory case of breast cancer with Cowden syndromePathological examinations of the core-biopsy specimen from the right breast before treatment (× 200 magnification). H&E staining shows invasive ductal carcinoma with high histological grade (a). ER staining was negative (b). HER2 staining was negative (c). Ki67 labeling index was more than 90% (d). Black bar represents 100 μm lengthBack to article page