Table 4 Complete case multivariate Cox proportional hazards model for disease-free survival
Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Gender | ||||||
Female | 1 | |||||
Male | 1.13 | 0.92–1.40 | NS | |||
Surgery | ||||||
Open | 1 | 1 | ||||
Laparoscopic | 0.68 | 0.49–0.94 | < 0.05 | 0.77 | 0.55–1.06 | NS |
T-stage | ||||||
T1–T3 | 1 | 1 | ||||
T4 | 1.33 | 1.04–1.71 | < 0.05 | 1.26 | 0.98–1.63 | NS |
N-stage | ||||||
N1 | 1 | 1 | ||||
N2 | 1.59 | 1.28–1.97 | < 0.01 | 1.60 | 1.29–2.00 | < 0.01 |
Differentiation | ||||||
High (G1–G2) | 1 | |||||
Low (G3–G4) | 1.16 | 0.91–1.49 | NS | |||
Mucinous | 1.25 | 0.80–1.95 | NS | |||
Tumor location | ||||||
Right sided | 1 | |||||
Left sided | 0.88 | 0.71–1.09 | NS | |||
Multiple locations | 0.75 | 0.28–2.03 | NS | |||
Adjuvant chemotherapy | ||||||
Yes | 1 | 1 | ||||
No | 2.02 | 1.63–2.49 | < 0.01 | 1.50 | 1.16–1.95 | < 0.01 |
Number of days in hospitala | 1.04 | 1.03–1.06 | < 0.01 | 1.03 | 1.01–1.05 | < 0.01 |
Age-adjusted Charlson Comorbidity Index | ||||||
0–2 | 1 | 1 | ||||
3–5 | 1.98 | 1.55–2.55 | < 0.01 | 1.59 | 1.20–2.11 | < 0.01 |
6–9 | 3.68 | 2.55–5.32 | < 0.01 | 2.40 | 1.57–3.67 | < 0.01 |
Clavien-Dindo | ||||||
0–3a | 1 | 1 | ||||
3b–4 | 1.61 | 1.10–2.35 | < 0.05 | 1.07 | 0.70–1.63 | NS |