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Table 2 The clinicopathological risk factors in patients with locally advanced cervical cancer

From: Neoadjuvant chemotherapy followed by radical surgery reduces radiation therapy in patients with stage IB2 to IIA2 cervical cancer

Variables NACT, N (%) PRS, N (%) P-value (χ2 test)
Total 197 217  
Preoperative tumor size    < 0.001
 ≤ 2.0 cm 71 (36.0) 43 (19.8)  
 2.1~4.0 cm 78 (39.6) 126 (58.1)  
 > 4.0 cm 48 (24.4) 48 (22.1)  
Parametrial involvement    0.776
 Negative 169 (85.8) 184 (84.8)  
 Positive 28 (14.2) 33 (15.2)  
Lymph node metastasis    0.336
 Negative 134 (68.0) 157 (72.4)  
 Positive 63 (32.0) 60 (27.6)  
LVSI    0.135
 Negative 150 (76.1) 151 (69.6)  
 Positive 47 (23.9) 66 (30.4)  
Cervical stromal invasion    0.023
 < 1/3 40 (20.3) 36 (16.6)  
 1/3~2/3 20 (10.2) 41 (18.9)  
 ≥ 2/3 72 (36.5) 88 (40.6)  
 Unknown 65 (33.0) 52 (24.0)  
Surgery margin    0.128
 Negative 190 (96.4) 202 (93.1)  
 Positive 7 (3.6) 15 (6.9)  
  1. NACT, neoadjuvant chemotherapy; PRS, primary radical surgery; LVSI, lymph vascular space invasion