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Table 3 Multivariate Cox regression analysis of potential prognostic factors for esophageal squamous cancer patients in the tissue microarray

From: Heparanase is a prognostic biomarker independent of tumor purity and hypoxia based on bioinformatics and immunohistochemistry analysis of esophageal squamous cell carcinoma

Patient characteristic

N

RR (95% CI)

p value

Gender

106

  

 Male

79

1

 

 Female

27

0.543 (0.309–0.956)

0.034*

T classification

106

  

 T1+T2

22

1

 

 T3+T4

84

1.817 (0.937–3.525)

0.077

N classification

106

  

 N0+N1

83

1

 

 N2+N3

23

1.492 (0.850–2.618)

0.163

Clinical stage

106

  

 I–II

52

1

 

 III–IV

54

1.915 (1.088–3.370)

0.024*

HPSE expression

106

  

 Low

88

1

 

 High

18

0.727 (0.375–1.412)

0.347

  1. RR relative risk, CI confidence interval
  2. *p < 0.05, **p < 0.01, ***p < 0.001