Table 2 Univariate Cox regression analysis of potential prognostic factors for esophageal squamous cancer patients in the tissue microarray

Gender

112

 Male

83

1

 Female

29

0.439 (0.258–0.747)

0.002**

Age (years)

111

 ≤66

57

1

 >66

54

1.052 (0.695–1.593)

0.811

T classification

106

 T1+T2

22

1

 T3+T4

84

2.710 (1.490–4.931)

0.001**

N classification

112

 N0+N1

88

1

 N2+N3

24

2.749 (1.680–4.498)

0.000***

Clinical stage

107

 I–II

52

1

 III–IV

55

3.127 (1.970–4.961)

0.000***

HPSE expression

112

 Low

93

1

 High

19

0.525 (0.286–0.965)

0.038*