Heparanase is a prognostic biomarker independent of tumor purity and hypoxia based on bioinformatics and immunohistochemistry analysis of esophageal squamous cell carcinoma

Table 1 Correlation between HPSE expression in cancerous tissues and clinicopathologic characteristics

Patient characteristic	N	Spearman R	p value
Gender	112	0.013	0.889
Male	83
Female	29
Age (years)	111	−0.041	0.673
≤67	57
>67	54
T classification	106	−0.132	0.177
T1	4
T2	18
T3	83
T4	1
N classification	112	−0.235	0.013*
N0	52
N1	36
N2	19
N3	5
Clinical stage	107	−0.218	0.024*
I	4
II	48
III	55
IV	0
Survival status	112	−0.120	0.208
Alive	21
Death	91

ISSN: 1477-7819