Fig. 7

HPSE expression in ESCC tumor tissues is associated with a poor prognosis. A A paired t test was used to compare the differences in HPSE protein levels between ESCC and matched para-carcinoma tissues. B Representative IHC images for high and low HPSE expression. The expression level of HPSE protein was quantified by using Image-Pro Plus 6.0 image analysis software. C Kaplan–Meier curves showed that patients with low HPSE levels in cancerous gastric tissues had poor overall survival