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Table 2 The chi-square test of the relation between risk score and clinical features in ICGC and GSE14520 cohort

From: Risk predictive model based on three immune-related gene pairs to assess prognosis and therapeutic sensitivity for hepatocellular carcinoma

Clinical features ICGC, n = 231 GSE14520, n = 242
High risk Low risk P High risk Low risk P
Survival status    0.04    0.04
 Survived 43 146   12 134  
 Died 16 26   16 80  
Age    0.63    0.17
 ≥ 60 years 49 138   3 47  
 < 60 years 10 34   25 167  
Sex    0.84    0.12
 Male 44 126   27 184  
 Female 15 46   1 30  
Stage    < 0.001    0.08
 I–II 25 116   18 156  
 III–IV 34 56   10 41  
 x 0 0   0 17  
Histological grade    < 0.01    
 G1–2 30 128     
 G3–4 21 33     
 Gx 8 11     
Cirrhosis status       0.37
 No cirrhosis     1 18  
 Cirrhosis     27 196  
Recurrence status       0.19
 No recurrence     9 97  
 Recurrence     19 117  
Hepatitis status       0.23
 Hepatitis B     27 191  
 No hepatitis     1 23  
  1. The cases with “Gx” and stage “x” were excluded from the chi-square test