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Table 3 Univariable analysis and Cox multivariate regression analysis for 7103 GCA patients

From: Transthoracic, thoracoabdominal, and transabdominal surgical approaches for gastric cardia adenocarcinomas: a survival evaluation based on a cohort of 7103 patients

Variable Univariable analysis Multivariable analysis
HR (95% CI) p-Value HR (95% CI) p-Value
Sex
 Female vs. male 0.90 (0.84–0.97) 0.004 0.88 (0.82–0.95)  < 0.001
Age (years)
 40–49 vs. < 40 0.79 (0.57–1.08) 0.14 0.89 (0.65–1.22) 0.46
 50–59 vs. < 40 0.93 (0.69–1.26) 0.63 1.05 (0.77–1.42) 0.76
 60–69 vs. < 40 1.15 (0.85–1.56) 0.36 1.31 (0.97–1.77) 0.08
 70–79 vs. < 40 1.64 (1.20–2.22) 0.002 1.87 (1.37–2.53)  < 0.001
  ≥ 80 vs. < 40 2.49 (1.65–3.75)  < 0.001 2.59 (1.72–3.91)  < 0.001
Tumor stage
 II vs. 0/I 1.54 (1.27–1.85)  < 0.001 1.56 (1.29–1.88)  < 0.001
 III vs. 0/I 2.54 (2.11–3.07)  < 0.001 2.60 (2.16–3.13)  < 0.001
 IV vs. 0/I 2.37 (1.87–3.01)  < 0.001 2.36 (1.86–3.00)  < 0.001
Surgical approach
 Thoracoabdominal vs. transthoracic 1.15 (1.06–1.25) 0.001 1.16 (1.07–1.26)  < 0.001
 Transabdominal vs. transthoracic 1.38 (1.21–1.56)  < 0.001 1.31 (1.16–1.49)  < 0.001
  1. 95% CI 95% confidence interval, HR hazard ratio