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Table 1 Clinical characteristics of breast cancer patients

From: GSTP1 c.313A > G mutation is an independent risk factor for neutropenia hematotoxicity induced by anthracycline-/paclitaxel-based chemotherapy in breast cancer patients

 

Number (mean ± SD)

Percentage (%)

Age (year)

 <35

16 (31.00 ± 2.68)

11.3

 35–50

60 (43.20 ± 4.70)

42.2

 >50

66 (57.47 ± 5.19)

46.5

Menopause

 No

83

58.5

 Yes

59

41.5

T-stage

 T0–T2

61

43.0

 T3–T4

81

57.0

N-stage

 N0–N1

43

30.3

 N2–N3

99

69.7

Clinical stage

 I–III

108

76.1

 IV

34

23.9

Molecular subtypes

 Luminal A

10

7.0

 Luminal B

77

54.2

 HER2 + 

33

23.2

 TNBC

22

15.5

Chemotherapy regimena

 TEC (docetaxel 75 mg/m2, epirubicin 75 mg/m2)

114

80.3

 EC-T/EC-TH (docetaxel 90 mg/m2, epirubicin 90 mg/m2)

23

16.2

 TCbH (taxane 175 mg/m2)

3

2.1

 TCb (taxane 175 mg/m2)

1

0.7

 EC (epirubicin 90 mg/m2)

1

0.7

  1. ER Estrogen receptor, PR Progesterone receptor; TNBC Triple-negative breast cancer
  2. aOnly the doses of anthracycline and paclitaxel in different regimens were shown