Table 1 Clinicopathological characteristics of 7478 Korean patients who met the Z0011 criteria
Total number (n = 7478) | SLNB + ALND (n = 4834) | SLNB alone (n = 2644) | p valuea | |
|---|---|---|---|---|
Age at surgery (years) | ||||
< 40 | 767 (10.3) | 486 (10.1) | 281 (10.6) | 0.738 |
40–49 | 2755 (36.9) | 1790 (37.0) | 965 (36.6) | |
50–59 | 2482 (33.2) | 1612 (33.4) | 870 (33.0) | |
60–69 | 1060 (14.2) | 690 (14.3) | 370 (14.0) | |
70–79 | 360 (4.8) | 227 (4.7) | 133 (5.0) | |
> 80 | 48 (0.6) | 27 (0.5) | 21 (0.8) | |
Unknown | 6 | 2 | 4 | |
Year of surgery | ||||
2011 | 1113 | 853 (76.6) | 260 (23.4) | < 0.0001 |
2012 | 1252 | 909 (72.6) | 343 (27.4) | |
2013 | 1278 | 891 (69.7) | 387 (30.3) | |
2014 | 1241 | 784 (63.2) | 457 (36.8) | |
2015 | 801 | 487 (60.8) | 314 (39.2) | |
2016 | 727 | 394 (54.2) | 333 (45.8) | |
2017 | 784 | 382 (48.7) | 402 (51.3) | |
2018 | 282 | 134 (47.5) | 148 (52.5) | |
pT | ||||
pT1 | 4156 (55.6) | 2490 (51.5) | 1666 (63.0) | < 0.0001 |
pT2 | 3322 (44.4) | 2344 (48.5) | 978 (37.0) | |
Number of resected nodes (median, range) | 12 (1–57) | 16 (5–57) | 5 (1–16) | < 0.0001 |
Number of positive lymph nodes (median, range) | 1 (1–25) | 2 (1–25) | 1 (1–3) | < 0.0001 |
pN | ||||
pN1 | 6381 (85.3) | 3779 (78.2) | 2602 (98.4) | < 0.0001 |
pN2 | 863 (11.5) | 827 (17.1) | 36 (1.4) | |
pN3 | 234 (3.2) | 228 (4.7) | 6 (0.2) | |
Multifocality | ||||
Single lesion | 5362 (91.7) | 3407 (91.2) | 1955 (92.5) | 0.094 |
Multifocal lesion | 487 (8.3) | 328 (8.8) | 159 (7.5) | |
Unknown | 1629 | 1099 | 530 | |
Histologic subtype | ||||
IDC | 6232 (83.3) | 4067 (84.1) | 2165 (81.9) | 0.013 |
Other | 1246 (16.7) | 767 (15.9) | 479 (18.1) | |
Histologic grade | ||||
I | 915 (13.8) | 600 (14.0) | 315 (13.5) | < 0.0001 |
II | 3605 (54.6) | 2235 (52.3) | 1370 (58.9) | |
III | 2085 (31.6) | 1442 (33.7) | 643 (27.6) | |
Unknown | 873 | 557 | 316 | |
Lymphatic invasion | ||||
No | 2899 (50.8) | 1731 (46.9) | 1168 (57.8) | < 0.0001 |
Yes | 2811 (49.2) | 1958 (53.1) | 853 (42.2) | |
Unknown | 1768 | 1145 | 623 | |
ER status | ||||
Negative | 1212 (18.0) | 843 (19.3) | 369 (15.5) | < 0.0001 |
Positive | 5534 (82.0) | 3516 (80.7) | 2018 (84.5) | |
Unknown | 732 | 475 | 257 | |
HER2 status | ||||
Negative | 5180 (83.2) | 3299 (81.9) | 1881 (85.5) | < 0.001 |
Positive | 1047 (16.8) | 728 (18.1) | 319 (14.5) | |
Unknown | 1251 | 807 | 444 | |
ER/HER2 status | ||||
ER + /HER2- | 4450 (71.5) | 2794 (69.4) | 1656 (75.3) | < 0.0001 |
HER2 + | 1047 (16.8) | 728 (18.1) | 319 (14.5) | |
ER-/HER2- | 729 (11.7) | 505 (12.5) | 224 (10.2) | |
Unknown | 1252 | 807 | 445 | |
TNBC | ||||
Yes | 670 (10.1) | 460 (10.7) | 210 (8.9) | 0.021 |
No | 5984 (89.9) | 3839 (89.3) | 2145 (91.1) | |
Unknown | 824 | 535 | 289 | |
Radiotherapy | ||||
Yes | 5697 (93.5) | 3649 (93.7) | 2048 (93.0) | 0.317 |
No | 398 (6.5) | 245 (6.3) | 153 (7.0) | |
Unknown | 1383 | 940 | 443 | |