Table 2 Univariable and multivariable analyses for PHLF grade B–C in the training cohort

Age, years

 − 0.001

0.961

0.999

0.975–1.024

NA

Male gender

 − 0.035

0.937

0.966

0.406–2.296

NA

ALT, U/L

0.006

0.055

1.006

1.000–1.011

NA

AST, U/L

0.015

0.001

1.015

1.007–1.023

NS

γ-GT, U/L

0.000

0.617

1.000

0.999–1.002

NS

PT, s

0.661

0.001

1.936

1.461–2.565

NS

INR 10x

0.914

0.001

2.493

1.733–3.506

0.529

0.005

1.698

1.198–2.501

Hilar occlusion ≥ 20 min

0.032

0.926

1.033

0.522–2.043

NA

Intraoperative blood loss ≥ 300 ml

1.439

0.001

4.219

2.262–7.866

1.082

0.004

2.952

1.430–6.235

Major resection

1.909

0.063

6.747

0.903–50.413

NA

Open hepatectomy

19.498

0.999

0.000

0.000–imponderable

NA

Cirrhosis

1.665

0.002

5.287

1.850–15.109

1.392

0.019

4.022

1.397–15.037

HBsAg positive

0.279

0.418

1.322

0.673–2.597

NA

HBeAg positive

1.024

0.005

2.785

1.370–5.662

NS

HBV DNA positive

0.268

0.402

1.307

0.699–2.443

NA

Multiple tumors

 − 0.179

0.554

0.836

0.463–1.511

NA

AFP, ng/mL

 < 20

0.168

-

20–400

 − 0.506

0.287

0.603

0.237–1.531

NA

 > 400

0.318

0.343

1.375

0.712–2.655

NA

mALBI grade

1

0.001

-

2a

1.315

0.001

3.724

1.791–7.744

1.087

0.009

2.966

1.297–6.765

2b

2.599

0.001

13.453

5.887–30.745

2.126

0.001

8.383

3.197–22.508

BCLC stage

A

0.642

-

B

 − 0.286

0.477

0.751

0.341–1.654

NA

C

 − 0.282

0.413

0.754

0.384–1.482

NA

Child–Pugh B class

2.426

0.001

11.310

3.908–32.732

1.343

0.044

3.830

1.057–14.844