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Table 1 Reported single cases of Metaplastic  carcinoma with squamous differentiation of the breast (n=10)

From: Metaplastic carcinoma of the breast with squamous differentiation: prognostic factors and multidisciplinary treatment

Case

Author, Year

Age

PL

Size (cm)

LNS

Radiological findings

Diagnostic

Surgery

CT

RT

IC

Distant metastatic

Survival (months)

1

Graziano et al, 2015 [12]

59

No

Large mass

Negative

Solid/Cystic mass. No mic

CNB

R0

Neoadjuvant

NR

Triple negative

No

NR

2

Jagtap et al, 2015 [7]

45

Nipple retraction

Two Masses 9, 3

Negative

High density masses

Surgical specimen

R0

NR

NR

ER,PR negative Her 2 positive

No

NR

3

Nguyen et al, 2015 [10]

47

No

4

Positive

NR

Surgical specimen

R0

Adyuvant

Yes

ER positive PR, Her 2 negative

Lung and brain

NR

4

Arafah et al, 2016 [6]

73

No

Mic

Negative

Extensive calcifications

CNB

R0

No

No

Triple negative

No

11 years Pure insitu variant

5

Punzo et al, 2017 [8]

75

Inflamed cystic lesion

5

Negative

Solid/Cystic mass. Mic

Surgical specimen

R0

Patient refused

No

Triple negative p:63 positive

No

12

6

Chahdi et al, 2018 [9]

44

Cyst lesion

5

Positive

Solid/Cystic mass. Abscess

CNB

R0

Adyuvant

Yes

Triple negative

No

9

7

Goto et al, 2018 [11]

42

No

Large mass T4

Positive

Solid mass

Surgical specimen

R1

Adyuvant

Yes

Triple negative

No

17

8

Hardy et al, 2019 [13]

44

No

11

Negative

Solid necrotic mass

Surgical specimen

R1

Patient refused

No

Triple negativep:63 positive

No

NR

9

Current case 1

39

Fibrocystic disease

5

Positive

Solid/Cystic mass

Surgical specimen

R1

Neoadjuvant

Yes

Triple negativep:63 positive

Lungs and liver

11

10

Current case 2

57

No

8

Positive

Solid mass. Mic

CNB

No

Neoadjuvant

Yes

Triple negative

Liver

19

  1. PL preexistent lesions, LNS Lymph node status, CT Chemotherapy, RT Radiotherapy, IC Immunohistochemical characteristics, Mic microcalcifications, CNB Core needle biopsy, R0 Complete resection, R1 Incomplete resection, NR Not reported, ER Estrogen receptor, PR Progesterone receptor