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Table 2 Sensitivity analysis of UCHL1 to commonly used drugs in the treatment of lung cancer

From: UCHL1 acts as a potential oncogene and affects sensitivity of common anti-tumor drugs in lung adenocarcinoma

Compound

RNA type

RNA molecule

Omics

Source

Spearman

P*

Perezone

mRNA

UCHL1

Expression

CellMiner

− 0.533803875

0.006029875

Caracemide

mRNA

UCHL1

Expression

CellMiner

− 0.482980911

0.007064843

Bafetinib

mRNA

UCHL1

Expression

CellMiner

− 0.479686548

0.01466201

Palbociclib

mRNA

UCHL1

Expression

CellMiner

− 0.407997669

0.031646287

Piperlongumine

mRNA

UCHL1

Expression

GDSC

0.08744003

0.035600008

Gefitinib

mRNA

UCHL1

Expression

GDSC

0.091381303

0.028871531

Embelin

mRNA

UCHL1

Expression

GDSC

0.097463539

0.047825308

Tipifarnib

mRNA

UCHL1

Expression

GDSC

0.110392871

0.019774916

Phenformin

mRNA

UCHL1

Expression

GDSC

0.110531447

0.001943254

Bosutinib

mRNA

UCHL1

Expression

GDSC

0.115226293

0.003381483

  1. *P < 0.05