Table 6 Core tip

Chemotherapy

Four to six course of treatment

TEC

The tumor wound was reduced and blood supply was reduced.

ECOG score ≤ 3

EC-T

TAC

Surgery

Preoperative

The blood supply of the flap was investigated by ultrasound Doppler.

Remove ulcer secretions for bacterial culture.

According to the results of bacterial culture, sensitive antibiotics were selected.

Excise tumor, repair defect and improve patient's physical condition..

Intraoperative

The excised tissue was sent for pathological and cryogenic examination.

Try to achieve negative margin.

The latissimus dorsi flap was designed according to the scope of resection.

Donor site suture, cannot suture skin graft.

Post-operation

Antibiotics were given according to the results of preoperative bacterial culture.

Continuous negative pressure drainage, drainage liquid less than 20 ml, remove the drainage tube.

Radiotherapy

Patients with lymph node metastasis were treated with radiotherapy in stage III and IV.

Reduce local tumor recurrence, reduce distant metastasis.

Endocrinotherapy

ER, PR-positive patients

Trastuzumab treatment

Patients with positive HER-2