Table 1 Differential expression of fibulin-3 in relation to patient’s age and sex and tumor grade and stage
Variable | No. of cases | Negative n | Positive — low expression n | Positive — high expression n | p-value | |
|---|---|---|---|---|---|---|
Age (years) | < 65 | 93 | 36 | 23 | 34 | 0.723 |
65–84 | 66 | 28 | 16 | 22 | ||
> 84 | 1 | 0 | 0 | 1 | ||
Gender | Male | 125 | 53 | 31 | 41 | 0.342 |
Female | 35 | 11 | 8 | 16 | ||
Tumor grade | I | 15 | 7 | 5 | 3 | 0.092 |
II | 96 | 44 | 22 | 30 | ||
III | 46 | 12 | 11 | 23 | ||
Tumor pathologic stage (pT) | pT1 | 50 | 22 | 17 | 11 | 0.008 |
pT2 | 87 | 37 | 19 | 31 | ||
pT3 | 23 | 5 | 3 | 15 | ||
Muscle invasion | Muscle invasive (pT2/T3) | 110 | 42 | 22 | 46 | 0.033 |
Muscle noninvasive (pT1) | 50 | 22 | 17 | 11 | ||
Overall stage | I | 50 | 22 | 17 | 11 | 0.020 |
II | 87 | 37 | 19 | 31 | ||
III | 21 | 5 | 3 | 13 | ||
IV | 2 | 0 | 0 | 2 | ||