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Table 1 Differential expression of fibulin-3 in relation to patient’s age and sex and tumor grade and stage

From: Significance of fibulin-3 expression in bladder cancer: a tissue microarray-based immunohistochemical study

Variable No. of cases Negative n Positive — low expression n Positive — high expression n p-value
Age (years) < 65 93 36 23 34 0.723
65–84 66 28 16 22
> 84 1 0 0 1
Gender Male 125 53 31 41 0.342
Female 35 11 8 16
Tumor grade I 15 7 5 3 0.092
II 96 44 22 30
III 46 12 11 23
Tumor pathologic stage (pT) pT1 50 22 17 11 0.008
pT2 87 37 19 31
pT3 23 5 3 15
Muscle invasion Muscle invasive (pT2/T3) 110 42 22 46 0.033
Muscle noninvasive (pT1) 50 22 17 11
Overall stage I 50 22 17 11 0.020
II 87 37 19 31
III 21 5 3 13
IV 2 0 0 2