Expression status of p53 and organic cation transporter 1 is correlated with poor response to preoperative chemotherapy in esophageal squamous cell carcinoma

Table 4 Multivariate analysis of predictors of histological response in the entire cohort

Parameters		OR (95% CI)	P-value
Model 1
Sex	Male vs. female	1.67 (0.84–3.32)	0.147
p53 expression	Wild type vs. mutant type	2.16 (1.15–4.07)	0.017*
OCT1 expression	High vs. low	2.02 (1.06–3.85)	0.032*
Model 2
Sex	Male vs. female	1.65 (0.82–3.33)	0.165
p53/OCT1 expression	Both p53^WT-ex and OCT1^High vs. either p53^MT-ex or OCT1^Low	3.79 (1.75–8.21)	< 0.001*

ISSN: 1477-7819