Fig. 3

GO and KEGG functional annotation analyses of 19 differentially expressed ferroptosis-related genes. A Bubble chart of significantly enriched GO term. B The circle shows the scatter map of the specified gene in each GO term. The red circles and blue circles represent upregulation and downregulation genes, respectively. The higher the Z-score value, the higher the enrichment pathway expression. C Bubble chart of significantly enriched KEGG pathways. D The circle shows the scatter map of the specified gene in each KEGG pathway. The red circles and blue circles represent upregulation and downregulation genes, respectively. The higher the Z-score value, the higher the enrichment pathway expression. E The pie chart of the correlation between differentially expressed FRGs and classical cancer pathways. Red color represents activates pathways and green color represents inhibits pathways. F Network diagram of the correlation between differentially expressed FRGs and classical cancer pathways. Red color represents activates pathways and blue color represents inhibits pathways