Skip to main content

Table 2 Logistic regression analysis of the risk factors for LM in CRC patients

From: Nomogram for predicting occurrence of synchronous liver metastasis in colorectal cancer: a single-center retrospective study based on pathological factors

Characteristics

Univariate analysis

Multivariate analysis

OR [95% CI]

P value

OR [95% CI]

P value

Age (years)

 < 60

0.966 [0.526–1.774]

0.912

  

 60–74

0.858 [0.469–1.572]

0.621

  

 ≥ 75

Ref

   

BMI

 < 25

1.151 [0.538–1.151]

0.538

  

 ≥ 25

Ref

   

Sex

 Male

1.004 [0.664–1.516]

0.987

  

 Female

Ref

   

Tumor site

 Right-sited colon

2.787 [1.764–4.402]

< 0.001

2.228 [1.272–3.901]

0.005

 Left-sited colon

1.446 [0.857–2.441]

0.168

1.635 [0.889–3.007]

0.114

 Rectum

Ref

 

Ref

 

Tumor size (cm)

 ≤ 5

0.670 [0.450–0.998]

0.049

1.033 [0.638–1.671]

0.896

 > 5

Ref

 

Ref

 

Tumor type

 Ulcer type

0.438 [0.096–2.009]

0.288

  

 Uplift type

0.226 [0.047–1.102]

0.066

  

 Infiltrating type

Ref

   

Grade

 I/II

Ref

 

Ref

 

 III/IV

2.793 [1.779–4.384]

< 0.001

0.982 [0.555–1.737]

0.949

Histology

 Adenocarcinoma

0.297 [0.083–1.055]

0.060

  

 Mucinous

0.421 [0.113–1.568]

0.197

  

 Others

Ref

   

T

 T1/T2

0.049 [0.007–0.354]

0.003

0.130 [0.017–1.014]

0.052

 T3

0.321 [0.203–0.507]

< 0.001

0.417 [0.245–0.710]

0.001

 T4

Ref

 

Ref

 

N

 N0

0.123 [0.077–0.199]

< 0.001

0.246 [0.128–0.472]

< 0.001

 N1

0.263 [0.156–0.443]

< 0.001

0.308 [0.165–0.573]

< 0.001

 N2

Ref

 

Ref

 

LNE

 < 12

0.920 [0.531–1.595]

0.767

  

 ≥ 12

Ref

   

Vascular invasion

 No

0.258 [0.171–0.387]

< 0.001

0.509 [0.306–0.846]

0.009

 Yes

Ref

 

Ref

 

Nerve invasion

 No

0.402 [0.253–0.637]

< 0.001

1.050 [0.594–1.856]

0.866

 Yes

Ref

 

Ref

 

Lymphatic invasion

 No

0.547 [0.367–0.817]

0.003

1.383 [0.810–2.363]

0.235

 Yes

Ref

 

Ref

 

CEA

 Positive

0.148 [0.095–0.232]

< 0.001

0.329 [0.198–0.545]

< 0.001

 Negative

Ref

 

Ref

 

CA199

 Positive

0.080 [0.052–0.123]

< 0.001

0.167 [0.103–0.270]

< 0.001

 Negative

Ref

 

Ref

Â