Fig. 2
From: miR-495-3p depresses cell proliferation and migration by downregulating HMGB1 in colorectal cancer
miR-495-3p suppresses the malignant phenotypes of CRC cells. A Relative CRC cell growth rates at 12 h, 24 h, 36 h, 48 h and 60 h after knockdown or upregulation of miR-495-3p were measured using a CCK-8 assay. B The effect of miR-495-3p on CRC cell proliferation was assessed by an Edu assay. C Relative Edu-positive cell numbers after miR-495-3p knockdown and overexpression. D Transwell assays were performed to evaluate cellular migration after miR-495-3p knockdown and overexpression. E Flow cytometry apoptosis experiments were used to measure the apoptosis rate of HT-29 and SW480 cells after miR-495-3p knockdown and overexpression. *p < 0.05, **p < 0.01 and ***p < 0.001