Table 3 Univariate and multivariate analysis of breast pCR in patients with ER+, Her2− breast cancer (n = 273)

Age, years (≥ 45 vs < 45)

0.957 (0.457–2.002)

0.907

–

BMI, kg/m² (≥ 24 vs < 24)

1.352 (0.680–2.687)

0.389

–

Tumor location (right vs left)

1.029 (0.518–2.044)

0.935

–

Menopausal status (premenopausal vs postmenopausal)

1.156 (0.574–2.327)

0.685

–

 PLR (≥ 117.88 vs < 117.88)

1.983 (0.940–4.183)

0.072

2.008 (0.855–4.719)

0.110

 NLR (≥ 2.46 vs < 2.46)

0.683 (0.340–1.374)

0.285

–

 FBG (≥ 1.73 vs < 1.73)

2.111 (0.616–7.231)

0.234

–

Tumor size, cm

0.998

–

 < 2

1 (reference)

 2 ~ 5

0.964 (0.344–2.702)

 > 5

0.973 (0.270–3.502)

Lymph node status (cNX vs cN0)

1.340 (0.670–2.680)

0.407

–

Blood supply (abundant vs poor)

1.026 (0.504–2.088)

0.943

–

Histological grade

0.005

0.359

 I

1 (reference)

1 (reference)

 II

1.203 (0.264–5.473)

0.969 (0.168–5.598)

 III

5.400 (1.008–28.928)

2.152 (0.291–15.904)

ER (%)

0.004

0.020

  [1, 10]

1 (reference)

1 (reference)

  [10, 30]

0.513 (0.113–2.322)

0.400 (0.074–2.169)

  [30, 50]

0.606 (0.166–2.215)

0.636 (0.151–2.670)

  [50, 70]

0.256 (0.073–0.901)

0.312 (0.071–1.367)

 > 70

0.145 (0.045–0.468)

0.140 (0.036–0.545)

PgR (%)

< 0.001

0.003

 Negative

1 (reference)

1 (reference)

  [1, 10]

2.006 (0.805–5.002)

4.790 (1.316–17.431)

 > 10

0.343 (0.147–0.799)

0.932 (0.272–3.191)

Ki-67 (%)

0.001

0.001

 < 20

1 (reference)

1 (reference)

  [20, 40]

3.032 (1.060–8.673)

4.290 (1.363–13.498)

  [40, 60]

8.320 (2.742–25.243)

11.174 (3.306–37.771)

 ≥ 60

6.857 (1.759–26.730)

9.262 (1.959–43.781)

P53 status (positive vs negative)

1.841 (0.774–4.380)

0.168

–