Fig. 2

Differentially methylated regions in patients and controls. a The genomic distributions of hypomethylated and hypermethylated DMRs in introns, intergenomic, exons, non-coding, promoters and other regions. b The distribution of DMRs mapped to the whole genome on different chromosomes in patients. c Heat map of total 8398 DMRs, including 1875 hypermethylated and 6523 hypomethylated. d Heat map of DMRs located in promoter regions in patients and controls, including 16 hypermethylated and 923 hypomethylated