Fig. 4

The PPI network of activated memory CD4 and CD8 T cell-related genes. The STRING database was used to analyze protein-protein interactions encoded by activated memory CD4 T cells and CD8 T cells. The PPI score was set as 0.7 (high-confidence value). Afterward, the PPI networks of activated memory CD4 T cells and CD8 T cell-related genes were constructed using Cytoscape software. PPI network analysis of activated memory CD4 T cell-related genes revealed 53 nodes and 162 interaction pairs. The CD8 T cell-related gene PPI network contained 127 nodes and 613 interaction pairs. A The PPI network of activated memory CD4 T cell-related genes. B The PPI network of CD8 T cell-related genes. Red nodes represent survival-related DEGs, triangles represent upregulated DEGs, and blue nodes represent other DEGs. The size of nodes represents the value. Larger nodes indicate a larger value. PPI, protein-protein interaction; STRING, Search Tool for the Retrieval of Interacting Genes