Fig. 8

CircVAPA silencing suppresses xenograft tumor growth in vivo. A Summary of tumor volume of nude mice was shown. B Tumor weight and representative pictures of xenograft in nude mice were presented. C The expression levels of circVAPA, miR-342-3p, and ZEB2 were estimated with RT-qPCR assay. D Western blot assay was used to measure the ZEB2 level, with GAPDH as control. E IHC assay was conducted to analyze the levels of proliferation-associated marker (Ki-67), metastasis-associated marker (E-cadherin), and pro-apoptotic protein (Bax) in xenograft tumor tissues. **P < 0.01, ***P < 0.001