Fig. 2

Knockdown of circVAPA inhibits the proliferation and induces the apoptosis of NSCLC cells. A, B The expression levels of circVAPA and VAPA were examined by RT-qPCR assay in A549 and H1299 cells transfected with sh-NC, sh-circVAPA#1, sh-circVAPA#2, or sh-circVAPA#3. C The cell viability of A549 and H1299 cells was measured by MTT assay. D Colony-forming ability of A549 and H1299 cells was assessed by colony-forming assay. E The flow cytometry assay was performed to measure cell apoptosis. F Western blot assay was conducted to measure the expression of proliferation-associated protein (Ki-67) and pro-apoptotic protein (Bax). **P < 0.01, ***P < 0.001