Table 2 Univariate and multivariate analyses of clinicopathological factors affecting HCC recurrence of patients after liver resection

Age (years)

0.832

-

 < 60

3.91

2.92–4.90

 ≥ 60

4.31

2.15–6.46

Gender

0.554

-

 Female

3.52

1.93–5.10

 Male

4.08

2.94–5.22

Hepatitis B virus

0.023

 Positive

3.09

2.62-3.56

1.32 (0.91–1.93)

0.144

 Negative

5.82

1.69–9.95

1

Hepatitis C virus

0.149

-

 Positive

5.72

0.27–11.17

 Negative

3.42

2.66–4.18

ICG 15 min (%)

0.936

-

 < 10

3.35

1.94-4.76

 ≥ 10

3.45

3.26–3.64

AFP (ng/ml)

0.426

-

 ≥ 400

5.82

4.12–7.52

 < 400

3.03

2.35–3.70

Tumor capsule

0.050

 Presence

5.20

4.11–6.28

1

 Absence

2.89

1.98–3.80

1.27 (0.87–1.87)

0.218

Satellite nodule

0.888

-

 Presence

3.55

2.42–4.68

 Absence

4.57

2.57–6.57

Extent of liver resection

0.662

-

 < 3 segments

3.03

2.00–4.05

 ≥ 3 segments

4.08

2.92–5.23

Resection margin

0.024

 < 0.5 cm

2.07

0.35–3.79

1.66 (1.07–2.56)

0.023

 ≥ 0.5 cm

4.57

3.37–5.77

1

Maximum tumor size

0.009

 < 5cm

11.47

3.01–19.94

1

 ≥ 5cm

3.39

2.65–4.12

1.61 (1.01–2.60)

0.044

Portal vein invasion

0.006

 Vp2

4.87

2.44–7.29

1

 Vp3

4.18

2.83–5.52

1.16 (0.79–1.69)

0.448

 Vp4

1.61

0.61–2.62

2.21 (1.15–4.24)

0.018