Table 2 Multivariate Cox analysis of factors associated with survival

3-year (%)

3-year (%)

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

No

68.7

Reference

Reference

26.7

Reference

Yes

51.5

2.006 (1.704–3.748)

0.029

2.472 (1.247–4.903)

0.010

17.4

1.613 (0.994–2.617)

0.053

Clinical N stage

0.001

0.007

N0

83.6

Reference

Reference

31.9

Reference

Reference

N1

66.2

2.504 (1.164–5.387)

0.019

2.834 (1.256–6.396)

0.012

21.3

1.342 (0.888–2.028)

0.163

1.342 (0.888–2.028)

0.163

N2

48.3

4.195 (1.972–8.924)

<0.01

4.602 (2.055–10.305)

<0.01

17.4

2.083 (1.353–3.206)

0.001

2.100 (1.364–3.231)

0.001

Fibrinogen (G/L)

≤3.41

80.2

Reference

Reference

27.6

Reference

> 3.41

55.1

2.777 (1.593–4.840)

<0.01

2.254 (1.246–4.078)

0.007

24.9

1.008 (0.720–1.409)

0.965

No

42.8

Reference

Reference

28.5

Reference

Yes

69.1

0.501 (0.261–0.960)

0.037

0.367 (0.148–0.908)

0.030

24.9

1.385 (0.798–2.404)

0.246

≤208.48

72.3

Reference

28.8

Reference

Reference

> 208.48

49.7

2.448 (1.448–4.028)

<0.01

2.396 (1.391–4.126)

0.002

13.4

1.414 (0.985–2.031)

0.061

1.371(0.953–1.972)

0.09