Table 3 Meta-analyses of miR-140 expression classified by clinicopathological parameters
Study covariates | Studies (patients) | OR (95% CI) | I2 (%) | Ph | Z | P | Model |
|---|---|---|---|---|---|---|---|
Gender (male/female) | 7 (770) | 1.068 (0.761-1.499) | 30.0 | 0.199 | 0.38 | 0.703 | Fixed |
Age (< 60/≥ 60) | 3 (257) | 0.859 (0.500-1.475) | 0.0 | 0.519 | 0.55 | 0.582 | Fixed |
Tumor size (≤ 5/> 5 cm) | 3 (257) | 1.152 (0.352-3.773) | 79.0 | 0.008 | 0.23 | 0.815 | Random |
TNM stage (1-2/3-4) | 6 (614) | 0.420 (0.299-0.590) | 43.4 | 0.113 | 5.00 | < 0.001 | Fixed |
LN metastasis (absence/presence) | 6 (568) | 0.341 (0.144-0.807) | 78.9 | < 0.001 | 2.45 | 0.014 | Random |
Histologic grade (well+ moderately differentiated/ poorly differentiated) | 4 (389) | 0.410 (0.261-0.643) | 0.0 | 0.552 | 3.88 | < 0.001 | Fixed |