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Table 3 Correlation analysis of DPYSL2 and related genes and immune cells markers in TIMER

From: DPYSL2 as potential diagnostic and prognostic biomarker linked to immune infiltration in lung adenocarcinoma

Description Gene markers Non-adjusted Tumor purity adjusted
Cor P value Cor P value
CD4+ T cell CD4 0.425 *** 0.412 ***
Th1 STAT4 0.154 ** 0.106 1.9e−02
  TNF 0.138 * 0.083 6.63e−02
  TBX21 0.105 1.71e−02 0.06 1.8e-01
Th2 STAT5A 0.334 *** 0.305 ***
  STAT6 0.333 *** 0.353 ***
  GATA3 0.126 * 0.071 1.17e−01
Tfh CCL13 0.307 *** 0.271 ***
  BCL6 0.272 *** 0.268 ***
  CCR5 0.218 *** 0.17 **
Th17 STAT3 0.35 *** 0.349 ***
  RORC 0.163 ** 0.194 ***
  IL17A − 0.094 3.32e−02 − 0.122 *
Treg STAT5B 0.374 *** 0.356 ***
  CCR8 0.219 *** 0.175 ***
  FOXP3 0.133 * 0.08 7.73e−02
T cell exhaustion HAVCR2 0.225 *** 0.187 ***
  GZMB − 0.262 *** − 0.333 ***
  CTLA4 0.07 1.15e−01 0.003 9.43e−01
  PDCD1 −0.044 3.19e−01 − 0.113 1.24e−02
CD8+ T cell CD8A −0.02 6.52e−01 − 0.08 7.73e−02
  CD8B −0.116 * − 0.17 **
M1 Macrophage IRF5 0.15 ** 0.118 *
  NOS2 0.13 * 0.116 1e−02
  PTGS2 0.106 1.65e−02 0.115 1.09e−02
M2 Macrophage MS4A4A 0.306 *** 0.28 ***
  CD163 0.291 *** 0.267 ***
  VSIG4 0.241 *** 0.215 ***
Neutrophil CEACAM8 0.428 *** 0.428 ***
  ITGAM 0.383 *** 0.362 ***
  CCR7 0.266 *** 0.229 ***
Dendritic cell CD1C 0.522 *** 0.499 ***
  HLA-DPB1 0.405 *** 0.388 ***
  HLA-DPA1 0.401 *** 0.382 ***
  ITGAX 0.29 *** 0.268 ***
TAM CD68 0.234 *** 0.212 ***
  IL10 0.164 ** 0.114 1.13e−02
  CCL2 0.162 ** 0.113 1.17e−02
B cell CD27 0.077 8.08e−02 0.027 5.48e−01
  CD19 0.057 1.94e−01 0.009 8.38e−01
  CD79A 0.052 2.34e−01 0.011 8.11e−01
  1. Cor correlation coefficient; *P < 0.05, **P < 0.01, ***P < 0.001