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Table 3 Correlation analysis of DPYSL2 and related genes and immune cells markers in TIMER

From: DPYSL2 as potential diagnostic and prognostic biomarker linked to immune infiltration in lung adenocarcinoma

Description

Gene markers

Non-adjusted

Tumor purity adjusted

Cor

P value

Cor

P value

CD4+ T cell

CD4

0.425

***

0.412

***

Th1

STAT4

0.154

**

0.106

1.9e−02

 

TNF

0.138

*

0.083

6.63e−02

 

TBX21

0.105

1.71e−02

0.06

1.8e-01

Th2

STAT5A

0.334

***

0.305

***

 

STAT6

0.333

***

0.353

***

 

GATA3

0.126

*

0.071

1.17e−01

Tfh

CCL13

0.307

***

0.271

***

 

BCL6

0.272

***

0.268

***

 

CCR5

0.218

***

0.17

**

Th17

STAT3

0.35

***

0.349

***

 

RORC

0.163

**

0.194

***

 

IL17A

− 0.094

3.32e−02

− 0.122

*

Treg

STAT5B

0.374

***

0.356

***

 

CCR8

0.219

***

0.175

***

 

FOXP3

0.133

*

0.08

7.73e−02

T cell exhaustion

HAVCR2

0.225

***

0.187

***

 

GZMB

− 0.262

***

− 0.333

***

 

CTLA4

0.07

1.15e−01

0.003

9.43e−01

 

PDCD1

−0.044

3.19e−01

− 0.113

1.24e−02

CD8+ T cell

CD8A

−0.02

6.52e−01

− 0.08

7.73e−02

 

CD8B

−0.116

*

− 0.17

**

M1 Macrophage

IRF5

0.15

**

0.118

*

 

NOS2

0.13

*

0.116

1e−02

 

PTGS2

0.106

1.65e−02

0.115

1.09e−02

M2 Macrophage

MS4A4A

0.306

***

0.28

***

 

CD163

0.291

***

0.267

***

 

VSIG4

0.241

***

0.215

***

Neutrophil

CEACAM8

0.428

***

0.428

***

 

ITGAM

0.383

***

0.362

***

 

CCR7

0.266

***

0.229

***

Dendritic cell

CD1C

0.522

***

0.499

***

 

HLA-DPB1

0.405

***

0.388

***

 

HLA-DPA1

0.401

***

0.382

***

 

ITGAX

0.29

***

0.268

***

TAM

CD68

0.234

***

0.212

***

 

IL10

0.164

**

0.114

1.13e−02

 

CCL2

0.162

**

0.113

1.17e−02

B cell

CD27

0.077

8.08e−02

0.027

5.48e−01

 

CD19

0.057

1.94e−01

0.009

8.38e−01

 

CD79A

0.052

2.34e−01

0.011

8.11e−01

  1. Cor correlation coefficient; *P < 0.05, **P < 0.01, ***P < 0.001