Table 2 Cox analyses (univariate and multivariate) of overall survival in the TCGA-LUAD cohort

Age (< 65 vs > 65 years)

1.097 (0.781–1.540)

0.594

Gender

 Female vs male

1.059 (0.756–1.483)

0.739

Stage

 I vs II vs III vs IV

1.577 (1.348–1.845)

< 0.001

1.352 (0.902–2.025)

0.144

T classification

 T1 vs T2 vs T3 vs T4

1.579 (1.296–1.923)

< 0.001

1.278 (1.016–1.608)

0.036

N classification

 N0 vs N1 vs N2 vs N3

1.706 (1.405–2.072)

< 0.001

1.208 (0.858–1.701)

0.278

M classification

 M0 vs M1

1.843 (1.038–3.272)

0.037

0.912 (0.330–2.517)

0.858

DPYSL2 expression

 High vs low

0.760 (0.637–0.906)

0.002

0.778 (0.648–0.934)

0.007