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Table 2 Variables associated with OS according to the Cox PH regression model

From: A novel nomogram based on cardia invasion and chemotherapy to predict postoperative overall survival of gastric cancer patients

Variable Univariable analysis Multivariable analysis
HR 95% CI P-value HR 95% CI P-value
Age, years
 < 70 Ref    Ref   
 ≥ 70 1.526 1.419–1.642 < 0.001 1.671 1.546–1.806 < 0.001
Sex
 Male Ref      
 Female 0.973 0.903–1.049 0.476    
Race
 White Ref    Ref   
 Black 1.043 0.934–1.163 0.456 1.079 0.965–1.207 0.183
 Other 0.806 0.738–0.880 < 0.001 0.857 0.783–0.939 0.001
Location
 Cardia Ref    Ref   
 Non-cardia 0.906 0.835–0.983 0.018 0.762 0.699–0.831 < 0.001
Grade
 Well Ref    Ref   
 Moderately 1.515 1.182–1.942 0.001 0.972 0.756–1.249 0.824
 Poorly 2.064 1.624–2.623 < 0.001 1.153 0.902–1.474 0.257
T stage
 T1 Ref    Ref   
 T2 2.903 2.515–3.349 < 0.001 2.04 1.741–2.389 < 0.001
 T3 3.896 3.371–4.504 < 0.001 2.265 1.919–2.674 < 0.001
 T4 5.31 4.547–6.201 < 0.001 2.683 2.242–3.210 < 0.001
N stage
 N0 Ref    Ref   
 N1 2.051 1.828–2.302 < 0.001 1.981 1.749–2.243 < 0.001
 N2 3.527 3.147–3.952 < 0.001 3.308 2.912–3.758 < 0.001
 N3 5.446 4.861–6.102 < 0.001 4.431 3.876–5.065 < 0.001
M stage
 M0 Ref    Ref   
 M1 2.891 2.611–3.200 < 0.001 1.888 1.698–2.099 < 0.001
Tumor size, mm
 < 2 Ref    Ref   
 2~10 2.477 2.122–2.892 < 0.001 1.158 0.980–1.369 0.085
 ≥ 10/diffuse 4.632 3.861–5.558 < 0.001 1.57 1.289–1.913 < 0.001
Chemotherapy
 No/unknown Ref    Ref   
 Yes 0.936 0.870–1.006 0.073 0.556 0.513–0.602 < 0.001
  1. HR hazard ratio, CI confidence interval, Ref reference