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Fig. 6 | World Journal of Surgical Oncology

Fig. 6

From: Identification and verification of HCAR3 and INSL5 as new potential therapeutic targets of colorectal cancer

Fig. 6

Over-expression of INSL5 inhibited tumor cell proliferation. a Expression of INSL5 and RXFP4 in CRC cells. b, c Stable overexpression for INSL5 by retroviral transfection in HT29 and SW620 cells. d, e Results of CCK-8 assays indicated that INSL5 significantly inhibited proliferation. f Results of cell cycle in SW620. gi Results of cell apoptosis in SW620. The experiments were repeated thrice and similar results were obtained. Representative data was shown. Each assay was performed at least in triplicate. *, P =  < 0.05; **, P =  < 0.01; ***, P =  < 0.001

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