Table 4 Relationship between mutation of EGFR gene in exon E20 and clinical parameters
|  | Clinical parameters | No. | EGFR-E20 | Positive rate (%) | χ2 | p value | |
|---|---|---|---|---|---|---|---|
Wild type | Mutant type | ||||||
Age | ≤60 | 112 | 104 | 5 | 4.46 | 1.538 | 0.463 |
>60 | 109 | 100 | 3 | 2.75 | |||
Gender | Male | 114 | 103 | 4 | 3.51 | 2.578 | 0.276 |
Female | 107 | 101 | 4 | 3.74 | |||
Sample type | Tissue sample | 194 | 178 | 8 | 4.12 | 1.392 | 0.845 |
Whole blood sample | 22 | 21 | 0 | 0 | |||
Whole blood + tissue sample | 5 | 5 | 0 | 0 | |||
Pathological type | Squamous cell carcinoma | 15 | 13 | 0 | 0 | 9.188 | 0.163 |
Adenocarcinoma | 155 | 146 | 5 | 3.23 | |||
Adenosquamous carcinoma | 7 | 5 | 1 | 14.29 | |||
Staging | Stage IA | 22 | 22 | 0 | 0 | 17.414 | 0.235 |
Stage IB | 51 | 48 | 2 | 3.92 | |||
Stage IIA | 8 | 7 | 1 | 12.50 | |||
Stage IIB | 9 | 8 | 0 | 0 | |||
Stage IIIA | 23 | 21 | 0 | 0 | |||
Stage IIIB | 5 | 3 | 1 | 20.00 | |||
Stage IV | 33 | 32 | 1 | 3.03 | |||
Treatment | Surgery | 67 | 63 | 2 | 2.99 | 2.131 | 0.907 |
Chemotherapy | 37 | 34 | 1 | 2.70 | |||
Surgery + chemotherapy | 66 | 59 | 4 | 6.06 | |||