Table 10 Relationship between mutation of PIK3CA gene in exon E20 and clinical parameters
|  | Clinical parameters | No. | PIK3CA-E20 | Positive rate (%) | χ2 | p value | |
|---|---|---|---|---|---|---|---|
Wild type | Mutant type | ||||||
Age | ≤60 | 112 | 83 | 1 | 0.89 | 1.127 | 0.569 |
>60 | 109 | 79 | 0 | 0 | |||
Gender | Male | 114 | 85 | 0 | 0 | 1.175 | 0.556 |
Female | 107 | 77 | 1 | 0.93 | |||
Sample type | Tissue sample | 194 | 139 | 0 | 0 | 12.794 | 0.012 |
Whole blood sample | 22 | 18 | 1 | 4.55 | |||
Whole blood + tissue sample | 5 | 5 | 0 | 0 | |||
Pathological type | Squamous cell carcinoma | 15 | 12 | 0 | 0 | 4.735 | 0.578 |
Adenocarcinoma | 155 | 112 | 0 | 0 | |||
Adenosquamous carcinoma | 7 | 5 | 0 | 0 | |||
Staging | Stage IA | 22 | 16 | 0 | 0 | 8.351 | 0.870 |
Stage IB | 51 | 36 | 0 | 0 | |||
Stage IIA | 8 | 6 | 0 | 0 | |||
Stage IIB | 9 | 8 | 0 | 0 | |||
Stage IIIA | 23 | 16 | 0 | 0 | |||
Stage IIIB | 5 | 4 | 0 | 0 | |||
Stage IV | 33 | 29 | 0 | 0 | |||
Treatment | Surgery | 67 | 51 | 0 | 0 | 5.927 | 0.431 |
Chemotherapy | 37 | 25 | 1 | 2.70 | |||
Surgery + chemotherapy | 66 | 50 | 0 | 0 | |||