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Fig. 5 | World Journal of Surgical Oncology

Fig. 5

From: In silico analysis of differentially expressed genesets in metastatic breast cancer identifies potential prognostic biomarkers

Fig. 5

Comparison of mRNA expression of four DOE-A and three DUE-A potential biomarker candidate genes between basal-like and/or triple-negative breast cancer and other subtypes of breast cancer. A RNA-seq data of four DOE-A genes were obtained from the Cancer Cell Line Encyclopedia (CCLE) and analyzed. N = 31 in BL/TNBC and N = 26 in luminal type cell lines. B RNA-seq data of three DUE-A genes were obtained from the Cancer Cell Line Encyclopedia (CCLE) were analyzed. N = 31 in BL/TNBC and N = 26 in luminal type cell lines. C RNA-seq data of four DOE-A genes from The Cancer Genome Atlas (TCGA) [58] were analyzed at bc-GenExMiner v4.3. N = 97 in BL/TNBC and N = 736 in non-BL/TNBC type breast cancer patient samples. D RNA-seq data of three DUE-A genes from The Cancer Genome Atlas (TCGA) [58] were analyzed at bc-GenExMiner v4.3. N = 97 in BL/TNBC and N = 736 in non-BL/TNBC type breast cancer patient samples. Statistical significances in A and B were determined by unpaired t-tests and those in C and D were determined by the pre-set analytic method of bc-GenExMiner

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