Fig. 3

LncRNA SDCBP2-AS1 regulates EPDR1 through suppression of miR-100-5p. A RT-qPCR detection of miR-100-5p in OC tissues and adjacent tissues (n = 71); B starBase prediction of the binding sites between lncRNA SDCBP2-AS1 and miR-100-5p; C verification of the relation between lncRNA SDCBP2-AS1 and miR-100-5p reflected by dual-luciferase reporter assay; D/E verification of the relation between lncRNA SDCBP2-AS1 and miR-100-5p in A2780 and SKOV3 cells reflected by RIP assay; F bioinformatics database prediction of the binding sites between EPDR1 and miR-100-5p; G verification of the relation between EPDR1 and miR-100-5p reflected by dual-luciferase reporter assay; * P < 0.05, ** P < 0.01. Repetition = 3 (C–G); Data were expressed in the form of mean ± standard deviation and analyzed by t test, one-way analysis of variance, and Tukey’s multiple comparison test