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Table 2 Short-term clinical outcomes of chemoradiation and surgery in the mistletoe and non-mistletoe groups

From: Effect of mistletoe extract on tumor response in neoadjuvant chemoradiotherapy for rectal cancer: a cohort study

Variables

MG (n = 15)

NMG (n = 37)

P-value

Dose of radiation (Gy)

50.4

50.4

n/a

Concurrent chemotherapy

  

1.000¶

 Capecitabine

15 (100)

36 (97.3)

 

 5-Fluorouracil

0

1 (2.7)

 

cT after NCRT

  

0.848¶

 cT0

1 (6.7)

1 (2.7)

 

 cT2

6 (40.0)

12 (32.4)

 

 cT3

7 (46.7)

21 (56.8)

 

 cT4

1 (6.7)

3 (8.1)

 

cN after NCRT

  

0.666¶

 cN0

7 (46.7)

14 (37.8)

 

 cN1

6 (40.0)

14 (37.8)

 

 cN2

2 (13.3)

9 (24.3)

 

Interval to surgery (weeks)

8.6 (6.1–12.9)

8.7 (5.9–14.1)

0.808†

Type of surgery

  

0.506¶

 Low anterior resection

3 (20.0)

8 (21.6)

 

 Ultra-low anterior resection

10 (66.7)

24 (64.9)

 

 Abdominoperineal resection

1 (6.7)

1 (2.7)

 

 Hartmann’s operation

0

3 (8.1)

 

 Transanal excision

1 (6.7)

1 (2.7)

 

Total operative time (h)

3.0 (0.8–4.1)

3.0 (0.2–5.7)

0.428†

Estimated blood loss (mL)

20.0 (3.0–150.0)

30.0 (0–250.0)

0.385†

Intraoperative transfusion

  

n/a

 Yes

0

0

 

 No

15 (100)

37 (100)

 

Length of hospital stay (days)

8 (4–37)

8 (5–51)

0.676†

  1. Data are presented as median (range) for continuous variables and n (%) for categorical variables
  2. †Mann–Whitney test; ¶chi-square test or Fisher’s exact test
  3. MG, mistletoe group; NMG, non-mistletoe group; NCRT, neoadjuvant chemoradiotherapy