Fig. 3

HIF-1 as an immediate target of miR-194-5p. a The target binding sequence of HIF-1 and miR-194-5p was predicted from the TargetScan database (http://www.targetscan.org). b A dual luciferase reporter assay was conducted to evaluate the luciferase activities of WT HIF-1 or MUT HIF-1 and miR-194-5p or miR-NC cotransfected A549 cells. Data are presented as the mean ± SD. ***P < 0.001